St Stephen's AIDS Trust

Past Publications

 

Publications 2009 - 2010

 

Publications 2008 - 2009

 

Publications 2007 - 2008

 

Publications 2005 - 2006

 

 
 
 

HIV, infectious diseases and epidemiology

Easterbrook PJ, Phillips AN, Hill T, Matthias R, Fisher M, Gazzard B, Gilson R, Scullard G, Johnson M, Dunn DT, Orkin C, Anderson J, Schwenk A, Leen C, Sabin CA; on behalf of the UK Collaborative HIV Cohort (CHIC) Study Steering Committee.
Patterns and predictors of the use of different antiretroviral drug regimens at treatment initiation in the UK.
HIV Med. 2008 Jan;9(1):47-56.
PMID: 18199172 [PubMed - in process]

Bansi LK, Benzie AA, Phillips AN, Portsmouth S, Hill T, Leen C, Schwenk A, Johnson M, Anderson J, Gilson R, Easterbrook P, Gazzard B, Fisher M, Orkin C, Porter K, Pillay D, Taylor GP, Walsh JC, Sabin CA; UK Collaborative HIV Cohort (UK CHIC) Study.
Are previous treatment interruptions associated with higher viral rebound rates in patients with viral suppression?
AIDS. 2008 Jan 30;22(3):349-56.
PMID: 18195561 [PubMed - in process]

Waters L, Nelson M, Mandalia S, Bower M, Powles T, Gazzard B, Stebbing J.
The risks and incidence of K65R and L74V mutations and subsequent virologic responses.
Clin Infect Dis. 2008 Jan 1;46(1):96-100.
PMID: 18171220 [PubMed - in process]

Phillips AN, Leen C, Wilson A, Anderson J, Dunn D, Schwenk A, Orkin C, Hill T, Fisher M, Walsh J, Pillay D, Bansi L, Gazzard B, Easterbrook P, Gilson R, Johnson M, Sabin CA; UK Collaborative HIV Cohort (CHIC) Study.
Risk of extensive virological failure to the three original antiretroviral drug classes over long-term follow-up from the start of therapy in patients with HIV infection: an observational cohort study.
Lancet. 2007 Dec 8;370(9603):1923-8.
PMID: 18068516 [PubMed - indexed for MEDLINE]

Waters LJ, Mandalia S, Gazzard B, Nelson M.
Prospective HLA-B*5701 screening and abacavir hypersensitivity: a single centre experience.
AIDS. 2007 Nov 30;21(18):2533-4.
PMID: 18025891 [PubMed - indexed for MEDLINE]

Porter K, Walker S, Hill T, Anderson J, Leen C, Johnson M, Gazzard B, Walsh J, Fisher M, Orkin C, Schwenk A, Gilson R, Easterbrook P, Delpech V, Sabin CA; on behalf of the UK CHIC Study Group. Changes in Outcome of Persons Initiating Highly Active Antiretroviral Therapy at a CD4 Count Less Than 50 Cells/mm3.
J Acquir Immune Defic Syndr. 2007 Oct 25; [Epub ahead of print]
PMID: 17971709 [PubMed - as supplied by publisher]

Teo E, Azwra A, Jones R, Gazzard BG, Nelson M.
Guillain-Barre syndrome following immune reconstitution after antiretroviral therapy for primary HIV infection.
J HIV Ther. 2007 Sep;12(3):62-3. No abstract available.
PMID: 17962793 [PubMed - in process]

Stebbing J, Nathan B, Jones R, McKenna A, Powles T, Bower M, Holmes P, Gazzard B, Nelson M.
Virological failure and subsequent resistance profiles in individuals exposed to atazanavir.
AIDS. 2007 Aug 20;21(13):1826-8.
PMID: 17690587 [PubMed - indexed for MEDLINE]

Phillips AN, Gazzard B, Gilson R, Easterbrook P, Johnson M, Walsh J, Leen C, Fisher M, Orkin C, Anderson J, Pillay D, Delpech V, Sabin C, Schwenk A, Dunn D, Gompels M, Hill T, Porter K, Babiker A; UK Collaborative HIV Cohort Study.  
Rate of AIDS diseases or death in HIV-infected antiretroviral therapy-naive individuals with high CD4 cell count.
AIDS. 2007 Aug 20;21(13):1717-21.
PMID: 17690569 [PubMed - indexed for MEDLINE]

Benzie AA, Bansi LK, Sabin CA, Portsmouth S, Hill T, Johnson M, Gilson R, Easterbrook P, Gazzard B, Fisher M, Orkin C, Dunn D, Delpech V, Taylor GP, Walsh JC, Phillips AN; United Kingdom Collaborative HIV Cohort (CHIC) Study Group.
Increased duration of viral suppression is associated with lower viral rebound rates in patients with previous treatment failures.
AIDS. 2007 Jul 11;21(11):1423-30.
PMID: 17589188 [PubMed - indexed for MEDLINE]

Wang J, Ozzard A, Nathan M, Atkins M, Nelson M, Gazzard B, Bower M.
The significance of Epstein-Barr virus detected in the cerebrospinal fluid of people with HIV infection.
HIV Med. 2007 Jul;8(5):306-11.
PMID: 17561877 [PubMed - indexed for MEDLINE]

Low EE, Nathan B, Killingley BM, Nelson M, Gazzard B.
Listeriosis associated with upper gastrointestinal endoscopy in an HIV-infected patient.
Int J STD AIDS. 2007 Jun;18(6):431-2.
PMID: 17609041 [PubMed - indexed for MEDLINE]

Phillips AN, Gazzard BG, Clumeck N, Losso MH, Lundgren JD.
When should antiretroviral therapy for HIV be started?
BMJ. 2007 Jan 13;334(7584):76-8. Review. No abstract available.
PMID: 17218713 [PubMed - indexed for MEDLINE]

Stebbing J, Bower M, Mandalia S, Nelson M, Gazzard B.
Highly active anti-retroviral therapy (HAART)-induced maintenance of adaptive but not innate immune parameters is associated with protection from HIV-induced mortality.
Clin Exp Immunol. 2006 Aug;145(2):271-6.
PMID: 16879246 [PubMed - indexed for MEDLINE]:

Steel A, Clark S, Teo I, Shaunak S, Nelson M, Gazzard B, Kelleher P.
No change to HIV-1 latency with valproate therapy.
AIDS. 2006 Aug 1;20(12):1681-2. No abstract available.
PMID: 16868456 [PubMed - indexed for MEDLINE]

Pollock K, Stebbing J, Bower M, Gazzard B, Nelson M.
Emtricitabine intolerance in treatment-experienced patients switched from lamivudine: a method of assessing toxicity.
J Antimicrob Chemother. 2006 Jul;58(1):227-8. Epub 2006 May 9. No abstract available.
PMID: 16684800 [PubMed - indexed for MEDLINE]

Price H, Jones R, Stevanovic M, Nelson M, Bower M, Mandalia S, Gazzard B.
Do the mutations M046I and I047A confer resistance to kaletra?
AIDS. 2006 Apr 4;20(6):950-1. No abstract available.
PMID: 16549987 [PubMed - indexed for MEDLINE]

Jones SP, Qazi N, Morelese J, Lebrecht D, Sutinen J, Yki-Jărvinen H, Back DJ, Pirmohamed M, Gazzard BG, Walker UA, Moyle GJ.
Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudine- and zidovudine-containing regimens.
J Acquir Immune Defic Syndr. 2005 Dec 15;40(5):565-72.
PMID: 16284533 [PubMed - indexed for MEDLINE]

Jones R, Sawleshwarkar S, Michailidis C, Jackson A, Mandalia S, Stebbing J, Bower M, Nelson M, Gazzard BG, Moyle GJ.
Impact of antiretroviral choice on hypercholesterolaemia events: the role of the nucleoside reverse transcriptase inhibitor backbone.
HIV Med. 2005 Nov;6(6):396-402.
PMID: 16268821 [PubMed - indexed for MEDLINE]

Stebbing J, Waters L, Mandalia S, Bower M, Nelson M, Gazzard B.
Hepatitis C virus infection in HIV type 1-infected individuals does not accelerate a decrease in the CD4+ cell count but does increase the likelihood of AIDS-defining events.
Clin Infect Dis. 2005 Sep 15;41(6):906-11. Epub 2005 Aug 5.
PMID: 16107994 [PubMed - indexed for MEDLINE]

Waters L, Stebbing J, Jones R, Mandalia S, Bower M, Stefanovic M, Nelson M, Gazzard B.
The effect of statins on HIV rebound and blips.
J Acquir Immune Defic Syndr. 2005 Aug 15;39(5):637-8. No abstract available.
PMID: 16044021 [PubMed - indexed for MEDLINE]

Tung MY, Mandalia S, Bower M, Gazzard B, Nelson M.
The durability of virological success of tenofovir and didanosine dosed at either 400 or 250 mg once daily.
HIV Med. 2005 May;6(3):151-4.
PMID: 15876280 [PubMed - indexed for MEDLINE]

Sproat M, Pozniak AL, Peeters M, Winters B, Hoetelmans R, Graham NM, Gazzard BG.
The influence of the M184V mutation in HIV-1 reverse transcriptase on the virological outcome of highly active antiretroviral therapy regimens with or without didanosine.
Antivir Ther. 2005;10(2):357-61.
PMID: 15865231 [PubMed - indexed for MEDLINE]

Latham V, Stebbing J, Mandalia S, Michailidis C, Davies E, Bower M, Gazzard B, Nelson M.
Adherence to trizivir and tenofovir as a simplified salvage regimen is associated with suppression of viraemia and a decreased cholesterol.
J Antimicrob Chemother. 2005 Jul;56(1):186-9. Epub 2005 May 23.
PMID: 15911551 [PubMed - indexed for MEDLINE]

Phillips AN, Dunn D, Sabin C, Pozniak A, Matthias R, Geretti AM, Clarke J, Churchill D, Williams I, Hill T, Green H, Porter K, Scullard G, Johnson M, Easterbrook P, Gilson R, Fisher M, Loveday C, Gazzard B, Pillay D; UK Collaborative Group on HIV Drug Resistance; UK CHIC Study Group.
Long term probability of detection of HIV-1 drug resistance after starting antiretroviral therapy in routine clinical practice.
AIDS. 2005 Mar 25;19(5):487-94.
PMID: 15764854 [PubMed - indexed for MEDLINE]

Coyne KM, Boffito M, Theobald N, Asboe D.
Simvastatin co-prescribed with protease inhibitors despite dangerous drug interactions.
Sex Transm Infect. 2007 Oct;83(6):498. No abstract available.
PMID: 17911146 [PubMed - indexed for MEDLINE]

Mihailidis C, Dunn D, Pillay D, Pozniak A.
Effect of isolated V118I mutation in reverse transcriptase on response to first-line antiretroviral therapy.
AIDS. 2008 Jan 30;22(3):427-30.

Waters LJ, Mackie NE, Pozniak A, Winston A.
Polymorphisms at position 245 of HIV reverse transcriptase do not accurately predict the presence of human leukocyte antigen B*5701.
Clin Infect Dis. 2007 Nov 1;45(9):1243-4; author reply 1244-5. No abstract available

Rajeswaran G, Becker JL, Michailidis C, Pozniak AL, Padley SP.
The radiology of IRIS (immune reconstitution inflammatory syndrome) in patients with mycobacterial tuberculosis and HIV co-infection: Appearances in 11 patients.
Clin Radiol. 2006 Oct;61(10):833-43.

Moyle GJ, Wildfire A, Mandalia S, Mayer H, Goodrich J, Whitcomb J, Gazzard BG.
Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection.
J Infect Dis. 2005 Mar 15;191(6):866-72. Epub 2005 Feb 11.
PMID: 15717260 [PubMed - indexed for MEDLINE]

Sproat M, Pozniak AL, Peeters M, Winters B, Hoetelmans R, Graham NM, Gazzard BG.
The influence of the M184V mutation in HIV-1 reverse transcriptase on the virological outcome of highly active antiretroviral therapy regimens with or without didanosine.
Antivir Ther. 2005;10(2):357-61.

Xu L, Pozniak A, Wildfire A, Stanfield-Oakley SA, Mosier SM, Ratcliffe D, Workman J, Joall A, Myers R, Smit E, Cane PA, Greenberg ML, Pillay D.
Emergence and evolution of enfuvirtide resistance following long-term therapy involves heptad repeat 2 mutations within gp41.
Antimicrob Agents Chemother. 2005 Mar;49(3):1113-9.

Cane P, Chrystie I, Dunn D, Evans B, Geretti AM, Green H, Phillips A, Pillay D, Porter K, Pozniak A, Sabin C, Smit E, Weber J, Zuckerman M; UK Group on Transmitted HIV Drug Resistance.
Time trends in primary resistance to HIV drugs in the United Kingdom: multicentre observational study.
BMJ. 2005 Dec 10;331(7529):1368. Epub 2005 Nov 18.
PMID: 16299012 [PubMed - indexed for MEDLINE]